Details for gene set HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	set03_truncNotch_versus_absentNotch
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION
Enrichment Score (ES)	0.7212895
Normalized Enrichment Score (NES)	2.2967403
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ALDOA	39	5.848	0.1143	Yes
2	GNPDA1	200	4.535	0.1960	Yes
3	PGAM2	216	4.414	0.2831	Yes
4	PGAM1	232	4.372	0.3693	Yes
5	PKM2	336	4.023	0.4439	Yes
6	ENO3	433	3.738	0.5131	Yes
7	ENO1	470	3.677	0.5844	Yes
8	TPI1	1231	2.726	0.5978	Yes
9	PFKM	1598	2.460	0.6271	Yes
10	GNE	1620	2.446	0.6747	Yes
11	GAPDHS	1867	2.293	0.7071	Yes
12	PFKL	2361	2.045	0.7213	Yes
13	PFKP	3081	1.754	0.7175	No
14	PGK2	6085	0.996	0.5759	No
15	PGK1	7733	0.661	0.5005	No
16	NPL	8541	0.480	0.4666	No
17	BPGM	9868	0.173	0.3988	No
18	ALDOB	9949	0.153	0.3975	No
19	ENO2	10667	-0.027	0.3595	No
20	ALDOC	12047	-0.381	0.2929	No
21	GNPDA2	15370	-1.507	0.1443	No
22	PKLR	15407	-1.519	0.1726	No

Fig 2: HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION: Random ES distribution
Gene set null distribution of ES for HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION